Chemosensory Perception Lab
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CURRICULUM VITAE
 
 
 
J. ENRIQUE COMETTO-MUÑIZ
 
 
 
AFFILIATION    
 
Chemosensory Perception Laboratory,
Department of Surgery (Otolaryngology)
University of California, San Diego,
Mail Code 0957
La Jolla, CA 92093-0957
 
 
 
Street address:

8950 Villa La Jolla Drive,
Suite C135
La Jolla, CA 92037
Telephone:
FAX:
e-mail:
(858) 622-5832
(858) 458-9417
ecometto@ucsd.edu
 
 
 
EDUCATION    
1977
Licentiate in Clinical Analysis Faculty of Pharmacy and Biochemistry
University of Buenos Aires.
1977 Biochemist Faculty of Pharmacy and Biochemistry,
University of Buenos Aires.
1986 Doctor in Biochemistry Faculty of Pharmacy and Biochemistry,
University of Buenos Aires.
 
ACADEMIC AND RESEARCH POSITIONS


Teaching Assistant (Undergraduate), Department of Vegetal Biochemistry, Faculty of Pharmacy and Biochemistry, University of Buenos Aires.
1976-1977

Teaching Assistant (Graduate) , Department of Pharmacology and Toxicology, Faculty of Pharmacy and Biochemistry, University of Buenos Aires.
1978-1980

Internal Fellow, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), República Argentina, with place of work at: Laboratorio de Investigaciones Sensoriales, CONICET - Faculty of Medicine, University of Buenos Aires.
1978-1980

External Fellow, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), República Argentina, with places of work at: John B. Pierce Foundation Laboratory, New Haven, Connecticut, USA (as Visiting Assistant Fellow), and Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, USA (as Post-Graduate Fellow).
1980-1982
1983 Internal Fellow, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), República Argentina, with place of work at: Laboratorio de Investigaciones Sensoriales, CONICET - School of Public Health, Faculty of Medicine, University of Buenos Aires.
1984-1988 Assistant Investigator , Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), República Argentina, with place of work at: Laboratorio de Investigaciones Sensoriales, CONICET - School of Public Health, Faculty of Medicine, University of Buenos Aires.
1985-1986 Chief of Teaching Assistants , Department of Biological and Health Sciences, Common Basic Course, University of Buenos Aires.
1986-1993 Adjunct Professor of Biological Chemistry , Department of Biological and Health Sciences, Common Basic Course, University of Buenos Aires.
1988-1991 Visiting Assistant Fellow , John B. Pierce Laboratory, New Haven, Connecticut, USA.
1988-1994 Associate Research Scientist in Epidemiology (Environmental Health Division), Department of Epidemiology and Public Health, Yale University School of Medicine.
1989-1993 Associate Investigator , Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), República Argentina, with place of work at: John B. Pierce Laboratory and Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA.
1991-1994 Assistant Fellow, John B. Pierce Laboratory, New Haven, Connecticut, USA.
1994-1995 Associate Project Scientist , Division of Otolaryngology, Department of Surgery, School of Medicine, University of California, San Diego, La Jolla, California, USA.
1996-2001 Associate Research Scientist , Division of Otolaryngology, Department of Surgery, School of Medicine, University of California, San Diego, La Jolla, California, USA.
2001-Present Research Scientist, Division of Otolaryngology, Department of Surgery, School of Medicine, University of California, San Diego, La Jolla, California, USA.
 
 
 
PROFESSIONAL SOCIETIES  
 
Asociación Bioquímica Argentina (ABA).
Association for Chemoreception Sciences (AChemS).
European Chemoreception Research Organization (ECRO).
Sociedad Científica Argentina.
International Society of Indoor Air Quality and Climate (ISIAQ).
Society of Toxicology.
AWARDS
 
 
Moskowitz Jacobs Inc. AChemS Award for Research Excellence In The Psychophysics of Taste And Smell, April 1993.
   
BIBLIOGRAPHY
Abstracts and Meeting Presentations

Cometto-Muñiz, J.E. Características de los componentes del Sabor. 1er Congreso Latinoamericano de Ciencia y Tecnología de Alimentos, November, 1979, Buenos Aires, Argentina.

Cometto-Muñiz, J.E. Odor, taste, and flavor perception of some flavoring agents. Abstracts of the III Annual Meeting of the Association for Chemoreception Sciences , Sarasota, Florida, USA, 1981.

Cometto-Muñiz, J.E. and Cain, W.S. Perception of nasal pungency in smokers and nonsmokers. Abstracts of the IV Annual Meeting of the Association for Chemoreception Sciences , Sarasota, Florida, USA, 1982, p. 5.

Cain, W.S. and Cometto-Muñiz, J.E. Temporal integration in the common chemical sense. Abstracts of the V annual Meeting of the Association for Chemoreception Sciences , Sarasota, Florida, USA, 1983, Abs.#15.

Rabin, M.D.; Cometto-Muñiz, J.E. and Cain, W.S. Retention of odorants by the human nose. Abstracts of the V Annual Meeting of the Association for Chemoreception Sciences , Sarasota, Florida, USA, 1983, Abs.#117.

 Cain, W.S.; Cometto-Muñiz, J.E.; Isseroff, R. and Rabin, M.D. Temporal characteristics of the common chemical sense in human beings. Proceedings of the Eighth International Symposium on Olfaction and Taste , Chemical Senses 8 (3):247, 1984.

 Calviño, A.M.; Rodríguez, M.B.; Cometto-Muñiz, J.E. and García-Medina, M.R. Influence of instruction on suprathreshold judgements of sweetness and bitterness, alone and mixed. Abstracts of the VII Annual Meeting of the Association for Chemoreception Sciences, Sarasota, Florida, USA, 1985, Abs.#29.

 Cometto-Muñiz, J.E.; García-Medina, M.R.; Calviño, A.M. and Hernández, S.M. Perceptual properties of pungent odorants. Abstracts of the IX Annual Meeting of the Association for Chemoreception Sciences , Sarasota, Florida, USA, 1987, Abs.#92.

 García-Medina, M.R.; Cometto-Muñiz, J.E. and Calviño, A.M. Trigeminal and topographical characteristics of odors. Abstracts of the IX Annual Meeting of the Association for Chemoreception Sciences , Sarasota, Florida, USA, 1987, Abs.#148.

 Calviño, A.M.; Cometto-Muñiz, J.E. and García-Medina, M.R. Perception of sweetness and bitterness in different vehicles. Abstracts of the X Annual Meeting of the Association for Chemoreception Sciences , Sarasota, Florida, USA, 1988, Abs.#205.

 Cometto-Muñiz, J.E. and Cain, W.S. Thresholds for odor and pungency. Chemical Senses 15 (5):560, 1990.

 Cain, W.S.; Cometto-Muñiz, J.E. and Mott, A.E. Update on trauma-induced smell loss. Gordon Research Conference on Chemical Senses: Taste and Smell, Plymouth State College-South, Plymouth, New Hampshire, USA, 1990.

 Cometto-Muñiz, J.E. and Cain, W.S. Physico-chemical basis for the production of nasal pungency in humans by non-reactive chemicals. Chemical Senses 16 (5):509-510, 1991.

 Cometto-Muñiz, J.E. and Cain, W.S. Nasal Pungency and Odor from Nonreactive Airborne Chemicals. Chemical Senses 17 (5):605-606, 1992.

 Cometto-Muñiz, J.E. and Cain, W.S. Effectiveness of Homologous Series of Nonreactive Airborne Chemicals in Evoking Nasal Irritation and Odor. Abstracts of the 22nd Annual Meeting of the Society for Neuroscience , Vol. 18, Part 1, Anaheim, California, 1992, Abs.#258.6.

 Cometto-Muñiz, J.E. and Cain, W.S. Common Chemical and Olfactory Responses To Homologous Alkylbenzenes. Chemical Senses 18 (5):540-541, 1993.

 Patterson, M.Q.; Stevens, J.C.; Cain, W.S. and Cometto-Muñiz, J.E. Detection Thresholds of an Olfactory Mixture and its Three Components. Chemical Senses 18 (5):611, 1993.

 Cain, W.S.; Gent, J.F. and Cometto-Muñiz, J.E. The National Geographic Smell Survey and Gas Warning Odor: Replication and Extension. Chemical Senses 18 (5):536-537, 1993.

 Cometto-Muñiz, J.E. and Cain, W.S. Perception of Mixtures of Airborne Chemicals by the Olfactory, Nasal Trigeminal, and Ocular Trigeminal Sensory Systems. Chemical Senses 19 (5):454-455, 1994.

 Cain, W.S.; Cometto-Muñiz, J.E.; Babbitt, R.R. and Gent, J.F. Sensitivity to Warning Agents for Natural Gas. Chemical Senses 19 (5):450, 1994.

 Cometto-Muñiz, J.E. Physicochemical Determinants and Functional Properties of the Senses of Irritation and Smell.Abstracts of the 11thOak Ridge National Laboratory Life Sciences Symposium: Indoor Air and Human Health Revisited: Bringing Selected Advances in Medical Science to the Indoor Air Quality Community , Knoxville, TN, USA, March 28-31, 1994.

 Cometto-Muñiz, J.E.; Cain, W.S.; Abraham, M.H. and Andonian-Haftvan, J. Description and Prediction of Human Nasal Pungency Thresholds by a Solvation Equation. Chemical Senses 20 (6):677, 1995.

 Cain, W.S., Leaderer, B.P., Cometto-Muñiz, J.E., Gent, J., Buck, M., Berglund, L.G., Mohsenin, V., Monahan, E., Ginsberg, G.L., Andrews, L.S., and Kjaergaard, J.S. Human reactions to one-hour exposures to methyl tertiary-butyl ether (MTBE). Proceedings of the Conference on MTBE and Other Oxygenates: A Research Update, 1995, pp. D-211 — D-239. Falls Church, VA: Environmental Protection Agency.

 Cometto-Muñiz, J.E. and Cain, W.S. Nasal Localization Thresholds in Normosmics Mirror Nasal Pungency Thresholds in Anosmics, for Homologous n-Alcohols. Chemical Senses 21 (5):588-589, 1996.

 Cain, W.S., Leaderer, B.P., Ginsberg, G.L., Andrews, L.S., Cometto-Muñiz, J.E., Gent, J.F.,Buck, M., Berglund, L.G., Moshenin, V., Monahan, E., and Kjaergaard, S. Human Reactions and Pharmacokinetic Response to Low Levels of the Gasoline Oxygenate Methyl Tertiary-Butyl Ether (MTBE). Chemical Senses 21 (5):583-584, 1996.

 Cometto-Muñiz, J.E. Separating the Trigeminal from the Olfactory Response of the Nose to Airborne Chemicals. 25th Anniversary Academic Conference of Otolaryngology-Head and Neck Surgery at the University of California, San Diego , La Jolla, California, USA, June 28, 1996.

 Cometto-Muñiz, J.E., Cain, W.S., Abraham, M.H., and Kumarsingh, R. Sensory properties of selected terpenes: Thresholds for odor, nasal pungency, nasal localization, and eye irritation. Chemical Senses 22 (6):663, 1997.

 Abraham, M.H., Kumarsingh, K., Cometto-Muñiz, J.E., and Cain, W.S. Draize eye scores and eye irritation thresholds can be combined into one QSAR. Chemical Senses 22 (6):635-636, 1997.

 Calviño, A.M., García, M., Mazzobre, V., Tamasi, O., and Cometto-Muñiz, J.E. Total intensity, saltiness, and pungency of NaCl and KCl presented singly and in mixtures. Chemical Senses 22 (6):655, 1997.

 Cometto-Muñiz, J.E., Cain, W.S., Abraham, M.H., and Kumarsingh, R. Olfactory and trigeminal detection of 1-butanol and 2-heptanone singly and in binary mixtures. Chemical Senses 23 (5):620, 1998.

 Cometto-Muñiz, J.E. Human olfactory and trigeminal chemosensitivity: Detection of single chemicals and binary mixtures. Workshop on Sensory Irritation (sponsored by the Center for Indoor Air Research). La Jolla, California, May 8-9, 1998.

 Cometto-Muñiz, J.E., Cain, W.S., Abraham, M.H., and Kumarsingh, R. Ocular trigeminal chemoreception: Comparison with nasal trigeminal chemoreception and development of a quantitative structure-activity relationship (QSAR). Chemical Senses 24 (5):544-545, 1999.

 Cometto-Muñiz, J.E., Cain, W.S., Abraham, M.H., and Gola, J.M.R. Stimulus-response functions for olfactory and trigeminal detectability: Probing into the rules of chemosensory agonism in binary mixtures. Chemical Senses 25 (5):623, 2000.

 Cain, W.S., Wise, P.M., Lee, N-S., Ahn, B-H., Schmidt, R., Cometto-Muñiz, J.E., Gola, J.M., Abraham. M.H. Pungency from esters: Correlations with physicochemical indices and correspondence with the negative mucosal potential. Chemical Senses 25 (5):624, 2000.

 Cain, W.S., Abraham, M.H., Cometto-Muñiz, E., de Wijk, R. and Jalowayski, A.A. Deciphering the impact of airborne chemicals on the person. International Journal of Psychology 35(3-4):283, Sp. Iss., Jun-Aug, 2000.

 Cometto-Muñiz, J.E., Cain, W.S., Abraham, M.H., and Gola, J.M.R. Trigeminal detectability of single chemicals and mixtures. Chemical Senses 26 (8):1045, 2001.

 Cometto-Muñiz, J.E., Cain, W.S., and Abraham, M.H. Olfactory detectability of single chemicals and mixtures. Abstracts of the XXIVth Annual Meeting of the Association for Chemoreception Sciences , Sarasota, Florida, USA, 2002, Abs.#287.

 Cometto-Muñiz, J.E., Cain, W.S., and Abraham, M.H. Degree of dose addition in chemosensory detectability of mixtures: A window into the breadth of chemical tuning in chemoreception. Abstracts of the XXVth Annual Meeting of the Association for Chemoreception Sciences , Sarasota, Florida, USA, 2003, Abs.#79.

 Cometto-Muñiz, J.E., Cain, W.S., and Abraham, M.H. Cut-off effect in eye irritation from vapor-phase homologous acetates. Abstracts of the XXVIth Annual Meeting of the Association for Chemoreception Sciences , Sarasota, Florida, USA, 2004, Abs.#67.

 Cometto-Muñiz, J.E., Cain, W.S., and Abraham, M.H. Quantification of the efficacy of vapors to elicit nasal chemesthesis in anosmics. Abstracts of the XXVIIth Annual Meeting of the Association for Chemoreception Sciences, Sarasota, Florida, USA, 2005, Abs.#267. Chemical Senses 30(5):A202-203, 2005.

 Cometto-Muñiz, J.E., Cain, W.S., and Abraham, M.H. Molecular determinants for detection of human eye irritation from homologous chemical vapors in acute exposures. The Toxicologist 90(1), 268, 2006. (Abstracts of the 45th Annual Meeting of the Society of Toxicology, San Diego, California, USA, 2006, Abs.#1312).

 Cometto-Muñiz, J.E., Cain, W.S., and Abraham, M.H. Concentration-detection functions for eye irritation from homologous n-alcohols approaching a cut-off point. Abstracts of the 28th Annual Meeting of the Association for Chemoreception Sciences, Sarasota, Florida, USA, 2006, Abs.#206. Chemical Senses 31(5):A59, 2006.

 Cometto-Muñiz, J.E., Cain, W.S., Abraham, M.H, and Sánchez-Moreno, R. Concentration-detection functions for odor from homologous n-alcohols. Abstracts of the 29th Annual Meeting of the Association for Chemoreception Sciences, Sarasota, Florida, USA, 2007, Abs.#534.
Articles and Book Chapters

Cometto-Muñiz, J.E. Características de los componentes del sabor. La Alimentación Latinoamericana, Año 14, No122, 44-50, 1980.

 Cometto-Muñiz, J.E. Odor, taste, and flavor perception of some flavoring agents. Chemical Senses 6 (3):215-223, 1981.

 Dunn, J.D.; Cometto-Muñiz, J.E. and Cain, W.S. Nasal reflexes: Reduced sensitivity to CO2irritation in cigarette smokers.Journal of applied Toxicology 2 (3):176-178, 1982.

 Cometto-Muñiz, J.E. and Cain, W.S. Perception of nasal pungency in smokers and nonsmokers. Physiology & Behavior 29 (4):727-731, 1982.

 Cometto-Muñiz, J.E. and Cain, W.S. Temporal integration of pungency. Chemical Senses 8 (4):315-327, 1984.

 Cometto-Muñiz, J.E. and Noriega, G. Gender differences in the perception of pungency. Physiology & Behavior 34 (3):385-389, 1985.

 Cometto-Muñiz, J.E.; García-Medina, M.R.; Calviño, A.M. and Noriega, G. Interactions between CO2 oral pungency and taste. Perception 16 (5):629-640, 1987.

 Cometto-Muñiz, J.E.; García-Medina, M.R. and Calviño, A.M. Perception of pungent odorants alone and in binary mixtures. Chemical Senses, 14 (1):163-173, 1989.

 Cometto-Muñiz, J.E. and Hernández, S.M. Odorous and pungent attributes of mixed and unmixed odorants. Perception & Psychophysics 47 (4):391-399, 1990.

 Calviño, A.M.; García-Medina, M.R. and Cometto-Muñiz, J.E. Interactions in caffeine-sucrose and coffee-sucrose mixtures: Evidence of taste and flavor suppression. Chemical Senses15 (5):505-519, 1990.

 Cometto-Muñiz, J.E. and Cain, W.S. Thresholds for odor and nasal pungency. Physiology & Behavior 48 (5):719-725, 1990.

Cometto-Muñiz, J.E. and Cain, W.S. Nasal Pungency, Odor, and Eye Irritation Thresholds for Homologous Acetates. Pharmacology, Biochemistry & Behavior 39 (4):983-989, 1991.

 Cometto-Muñiz, J.E. and Cain, W.S. Influence of Airborne Contaminants on Olfaction and the Common Chemical Sense. In Thomas V. Getchell, Richard L. Doty, Linda M. Bartoshuk and James B. Snow Jr. (Eds.) Smell and Taste in Health and Disease . Raven Press, New York, 1991, pp. 765-785.

 Cain, W.S. and Cometto-Muñiz, J.E. Sensory Irritation and Indoor Air Quality. In Gregory R. Lockhead (Ed.) Fechner Day '91 (Proceedings of the 7th Annual Meeting of the International Society for Psychophysics). International Society for Psychophysics, Durham, 1991, pp. 157-162.

 Cain, W.S., Cometto-Muñiz, J.E. and de Wijk, R.A. Techniques in the Quantitative Study of Human Olfaction. In Michael Serby and Karen Chobor (Eds.) The Science of Olfaction. Springer-Verlag, New York, 1992, pp. 279-308.

 Cometto-Muñiz, J.E. and Cain, W.S. Sensory Irritation: Relation to Indoor Air Pollution. Annals of the New York Academy of Sciences 641 :137-151, 1992.

 Cometto-Muñiz, J.E. and Cain, W.S. Efficacy of Volatile Organic Compounds in Evoking Nasal Pungency and Odor. Archives of Environmental Health 48 (5):309-314, 1993.

 Cain, W.S. and Cometto-Muñiz, J.E. Irritation and Odor: Symptoms of Indoor Air Pollution. In Jouni JK Jaakkola, Raija Ilmarinen, and Olli Seppänen (Eds.) Indoor Air '93: Vol. 1, Health Effects (Proceedings of the 6th International Conference on Indoor Air Quality and Climate). Indoor Air '93, Helsinki, 1993, pp. 21-31.

 Cometto-Muñiz, J.E. and Cain, W.S. Nasal Irritation and Odor from Homologous Series of Chemicals. In Jouni JK Jaakkola, Raija Ilmarinen, and Olli Seppänen (Eds.) Indoor Air '93: Vol. 1, Health Effects (Proceedings of the 6th International Conference on Indoor Air Quality and Climate). Indoor Air '93, Helsinki, 1993, pp. 561-566.

 Patterson, M.Q., Stevens, J.C., Cain, W.S. and Cometto-Muñiz, J.E. Detection Thresholds for an Olfactory Mixture and its Three Constituent Compounds. Chemical Senses 18 (6):723-734, 1993.

 Calviño, A.M., García-Medina, M.R., Cometto-Muñiz, J.E. and Rodríguez, M.B. Perception of Sweetness and Bitterness in Different Vehicles. Perception & Psychophysics 54 (6):751-758, 1993.

 Cometto-Muñiz, J.E. and Cain, W.S. Sensory Reactions of Nasal Pungency and Odor to Volatile Organic Compounds: The Alkylbenzenes. American Industrial Hygiene Association Journal 55 (9):811-817, 1994.

 Cometto-Muñiz, J.E. and Cain, W.S. Perception of odor and nasal pungency from homologous series of volatile organic compounds. Indoor Air 4 (3):140-145, 1994.

 Cometto-Muñiz, J.E. and Cain, W.S. Olfactory Adaptation. In Richard L. Doty (Ed.) Handbook of Olfaction and Gustation . Marcel Dekker, New York, 1995, pp. 257-281.

 Cain, W.S. and Cometto-Muñiz, J.E. Irritation and odor as indicators of indoor pollution. Occupational Medicine: State of the Art Reviews 10 (1):133-145, 1995.

 Cometto-Muñiz, J.E. and Cain, W.S. Relative sensitivity of the ocular trigeminal, nasal trigeminal, and olfactory systems to airborne chemicals. Chemical Senses 20 (2):191-198, 1995.

 Cometto-Muñiz, J.E. Using human panels for subjective evaluation of emissions from indoor activities and materials: Principles and state of technology. Report to the U.S. E.P.A. under Contract (Order) N° 2D2405NATA, Requisition/Reference N°FN24240, 1995.

 Cometto-Muñiz, J.E. and Cain, W.S. Mixtures of volatile organic compounds: Detection of odor, nasal pungency, and eye irritation. In Marco Maroni (Ed.) Proceedings of Healthy Buildings '95. An International Conference on Healthy Buildings in Mild Climate . Volume 1. Healthy buildings '95, Milan, 1995, pp. 171-182.

Cain, W.S., Leaderer, B.P., Ginsberg, G.L., Andrews, L.S., Cometto-Muñiz, J.E., Gent, J.F., Buck, M., Berglund, L.G., Mohsenin, V., Monahan, E. and Kjærgaard, S. Acute exposure to low-level methyl tertiary-butyl ether (MTBE): Human reactions and pharmacokinetic response. Inhalation Toxicology 8 :21-48, 1996.

 Cometto-Muñiz, J.E. and Cain, W.S. Physicochemical Determinants and Functional Properties of the Senses of Irritation and Smell. In Richard B. Gammage and Barry A. Berven (Eds.) Indoor Air and Human Health, 2nd Edition, CRC Lewis Publishers, Boca Raton, 1996, pp. 53-65.

 Abraham, M. H., Andonian-Haftvan, J., Cometto-Muñiz, J.E. and Cain, W.S. An analysis of nasal irritation thresholds using a new solvation equation. Fundamental and Applied Toxicology 31 :71-76, 1996.

 Cain, W.S. and Cometto-Muñiz, J.E. Sensory irritation potency of VOCs measured through nasal localization thresholds. In S. Yoshizawa, K. Kimura, K. Ikeda, S. Tanabe, and T. Iwata (Eds.) Indoor Air '96: Vol. 1 (Proceedings of the 7th International Conference on Indoor Air Quality and Climate). Indoor Air '96: Seec Ishibashi Inc. Japan, 1996, pp. 167-172.

 Cometto-Muñiz, J.E., Cain, W.S. and Hudnell, H.K. Agonistic sensory effects of airborne chemicals in mixtures: Odor, nasal pungency, and eye irritation. Perception & Psychophysics 59 (5):665-674, 1997.

 Cometto-Muñiz, J.E. Contaminación de ambientes interiores: Estimulación de los sentidos del olfato e irritación química. In: M. Guirao (Ed.) Procesos Sensoriales y Cognitivos . CONICET-Dunken, Buenos Aires, 1997, pp. 299-313.

 Cometto-Muñiz, J.E., Cain, W.S. and Abraham, M. H. Nasal pungency and odor of homologous aldehydes and carboxylic acids. Experimental Brain Research 118 (2):180-188, 1998.

 Cometto-Muñiz, J.E. and Cain, W.S. Trigeminal and olfactory sensitivity: Comparison of modalities and methods of measurement. International Archives of Occupational and Environmental Health 71 (2):105-110, 1998.

 Abraham, M.H., Kumarsingh, K., Cometto-Muñiz, J.E. and Cain, W.S. An algorithm for nasal pungency thresholds in man. Archives of Toxicology 72 (4):227-232, 1998.

 Abraham, M.H., Kumarsingh, R., Cometto-Muñiz, J.E. and Cain, W.S. A quantitative structure-activity relationship (QSAR) for a Draize eye irritation database. Toxicology in Vitro 12 (3):201-207, 1998.

 Abraham, M.H., Kumarsingh, R., Cometto-Muñiz, J.E. and Cain, W.S. Draize eye scores and eye irritation thresholds in man combined into one quantitative structure-activity relationship. Toxicology in Vitro 12 (4):403-408, 1998.

 Cometto-Muñiz, J.E., Cain, W.S., Abraham, M.H., and Kumarsingh, R. Trigeminal and olfactory chemosensory impact of selected terpenes. Pharmacology, Biochemistry and Behavior 60 (3):765-770, 1998.

 Cometto-Muñiz, J.E., Cain, W.S., Abraham, M.H., and Kumarsingh, R. Sensory properties of selected terpenes: Thresholds for odor, nasal pungency, nasal localization, and eye irritation. Annals of the New York Academy of Sciences 855 :648-651, 1998.

 Abraham, M.H., Kumarsingh, R., Cometto-Muñiz, J.E., and Cain, W.S. Draize eye scores and eye irritation thresholds in man can be combined into one QSAR. Annals of the New York Academy of Sciences 855 :652-656, 1998.

 Abraham, M.H., Kumarsingh, R., Cometto-Muñiz, J.E., Cain, W.S., Rosés, M., Bosch, E. and Díaz, M.L. The determination of solvation descriptors for terpenes, and the prediction of nasal pungency thresholds. Journal of the Chemical Society Perkin Transactions 2 , 2405-2411, 1998.

 Cometto-Muñiz, J.E., Cain, W.S., Abraham, M.H. and Gola, J.M.R. Chemosensory detectability of 1-butanol and 2-heptanone singly and in binary mixtures. Physiology and Behavior 67 (2):269-276, 1999.

 Cometto-Muñiz, J.E., Cain, W.S., Hiraishi, T., Abraham, M.H. and Gola, J.M.R. Comparison of two stimulus-delivery systems for measurement of nasal pungency thresholds. Chemical Senses 25 (3):285-291, 2000.

 Abraham, M.H., Gola, J.M.R., Kumarsingh, K., Cometto-Muñiz, J.E. and Cain, W.S. Connection between chromatographic data and biological data. Journal of Chromatography B 745 (1):103-115, 2000.

 Abraham, M.H., Benjelloun-Dakhama, N., Gola, J.M.R., Acree, W.E.Jr., Cain, W.S. and Cometto-Muñiz, J.E. Solvation descriptors for ferrocene, and the estimation of some physicochemical and biochemical properties. New Journal of Chemistry 24 :825-829, 2000.

 Abraham, M.H., Gola, J.M.R., Cometto-Muñiz, J.E. and Cain, W.S. The solvation properties of nitric oxide. Journal of the Chemical Society Perkin Transactions 2 : 2067-2070, 2000.

 Cometto-Muñiz, J.E. Physicochemical basis for odor and irritation potency of VOCs. In: J.D. Spengler, J. Samet, and J.F. McCarthy (Eds.) Indoor Air Quality Handbook. McGraw-Hill, New York, 2001, pp. 20.1–20.21.

 Abraham, M.H., Gola, J.M.R., Cometto-Muñiz, J.E. and Cain, W.S. Solvation properties of refrigerants, and the estimation of their water-solvent and gas-solvent partitions. Fluid Phase Equilibria 180 (1-2): 41-58, 2001.

 Cometto-Muñiz, J. E., Cain, W. S., Abraham, M. H., and Gola, J. M. R. Ocular and nasal trigeminal detection of butyl acetate and toluene presented singly and in mixtures. Toxicological Sciences 63 :233-244, 2001.

 Abraham, M.H., Gola, J.M.R., Cometto-Muñiz, J.E., and Cain, W.S. The correlation and prediction of VOC thresholds for nasal pungency, eye irritation and odour in humans. Indoor and Built Environment 10 :252-257, 2001.

 Cometto-Muñiz, J.E., Cain, W.S., Abraham, M.H., and Gola, J.M.R. Psychometric functions for the olfactory and trigeminal detectability of butyl acetate and toluene. Journal of Applied Toxicology 22 :25-30, 2002.

 Abraham, M.H., Gola, J.M.R., Cometto-Muñiz, J.E. and Cain, W.S. A model for odor thresholds. Chemical Senses 27(2):95-104, 2002.

 Cometto-Muñiz, J.E., Cain, W.S., Abraham, M.H. and Gola, J.M.R. Sensory detection of VOCs singly and in mixtures: Odor and sensory irritation. In H. Levin (ed.): Indoor Air 2002. Proceedings of the 9th International Conference on Indoor Air Quality and Climate , Vol. 2. Indoor Air 2002, Santa Cruz, California, 2002, pp. 237-242.

 Cometto-Muñiz, J.E. Chemical sensing in humans and machines. In T.C. Pearce, S.S. Schiffman, H.T. Nagle and J.W. Gardner (eds.): Handbook of Machine Olfaction: Electronic Nose Technology , Wiley-VCH, Weinheim, 2003, pp. 33-53.

 Cometto-Muñiz, J.E., Cain, W.S. and Abraham, M.H. Dose-addition of individual odorants in the odor detection of binary mixtures. Behavioural Brain Research, 138 :95-105, 2003.

 Doty, R.L. and Cometto-Muñiz, J.E. Trigeminal chemosensation. In R.L. Doty (ed.): Handbook of Olfaction and Gustation (2nd Edition), Marcel Dekker, New York, 2003, pp. 981-1000.

 Cometto-Muñiz, J.E., Cain, W.S. and Abraham, M.H. Quantification of chemical vapors in chemosensory research. Chemical Senses, 28 (6):467-477, 2003.

 Abraham, M.H., Hassanisadi, M., Jalali-Heravi, M., Ghafourian, T., Cain, W.S. and Cometto-Muñiz, J.E. Draize rabbit eye test compatibility with eye irritation thresholds in humans: A quantitative structure-activity relationship analysis. Toxicological Sciences, 76 :384-391, 2003.

 Doty, R.L., Cometto-Muñiz, J.E., Jalowayski, A.A., Dalton P., Kendal-Reed, M. and Hodgson, M. Assessment of upper respiratory tract and ocular irritative effects of volatile chemicals in humans. Critical Reviews in Toxicology , 34 (1):1-58, 2004.

 Cometto-Muñiz, J.E., Cain, W.S. and Abraham, M.H. Chemosensory additivity in trigeminal chemoreception as reflected by detection of mixtures. Experimental Brain Research , 158 :196-206, 2004.

Witherspoon, J.R., Adams, G., Cain, W., Cometto-Muñiz, E. Forbes, B., Hentz, L., Novack, J.T. Higgins, M. Murthy, S., McEwen, D., Ong, H.T. and Daigger, G.T. Water Environment Research Foundation (WERF) anaerobic digestion and related processes, odour and health effects study. Water Science and Technology 50(4):9-16, 2004.

Cain, W.S. and Cometto-Muñiz, J.E. Health Effects of Biosolids Odors: A Literature Review. (Report 00-HHE-5C.) Identifying and Controlling Odor in the Municipal Wastewater Enivronment. Water Environment Research Foundation-IWA Publishing, 2004.

Cometto-Muñiz, J.E., Cain, W.S., and Abraham, M.H. (2004). Detection of single and mixed VOCs by smell and by sensory irritation. Indoor Air, 14(Suppl. 8):1080-117, 2004. 

Cometto-Muñiz, J.E., Cain, W.S. and Abraham, M.H. Odor detection of single chemicals and binary mixtures. Behavioural Brain Research, 156:115-123, 2005.

Cometto-Muñiz, J.E., Cain, W.S. and Abraham, M.H. Molecular restrictions for human eye irritation by chemical vapors. Toxicology and Applied Pharmacology, 2005.

Cometto-Muñiz, J.E., Cain, W.S., and Abraham, M.H. Determinants for nasal trigeminal detection of volatile organic compounds. Chemical Senses, 30:627-642, 2005.

Cometto-Muñiz, J.E., Cain, W.S., Abraham, M.H., and Sánchez-Moreno, R. Chemical boundaries for detection of eye irritation in humans from homologous vapors. Toxicological Sciences, 2006.

Cain, W.S., Lee, N.-S., Wise, P.M., Schmidt, R., Ahn, B.-H., Cometto-Muñiz, J.E. and Abraham, M.H. Chemesthesis from volatile organic compounds: Psychophysical and neural responses. Physiology and Behavior, 2006.

Cometto-Muñiz, J.E., Cain, W.S., Abraham, M.H. and Sánchez-Moreno, R. (2007) Cut-off in detection of eye irritation from vapors of homologous carboxylic acids and aliphatic aldehydes. Neuroscience, 145:1130-1137, 2007.

Cometto-Muñiz, J.E., Cain, W.S., Abraham, M.H. and Sánchez-Moreno, R. Concentration-detection functions for eye irritation evoked by homologous n-alcohols and acetates approaching a cut-off point. Experimental Brain Research, 2007, DOI 10.1007/s00221-007-0966-4.

Abraham, M.H., Sánchez-Moreno, R., Cometto-Muñiz, J.E., and Cain, W.S. A Quantitative Structure-Activity Analysis on the Relative Sensitivity of the Olfactory and the Nasal Trigeminal Chemosensory Systems. Chemical Senses, 2007 (in press).
      

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